martes, 25 de diciembre de 2012

National Guideline Clearinghouse | Evidence-based guidelines from ESPGHAN and NASPGHAN for Helicobacter pylori infection in children.

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National Guideline Clearinghouse | Evidence-based guidelines from ESPGHAN and NASPGHAN for <em>Helicobacter pylori</em> infection in children.


National Guideline Clearinghouse (NGC)

December 24, 2012

Guideline Title
Evidence-based guidelines from ESPGHAN and NASPGHAN for Helicobacter pylori infection in children.
 
 
Bibliographic Source(s)
Koletzko S, Jones NL, Goodman KJ, Gold B, Rowland M, Cadranel S, Chong S, Colletti RB, Casswall T, Elitsur Y, Guarner J, Kalach N, Madrazo A, Megraud F, Oderda G, H pylori Working Groups of ESPGHAN and NASPGHAN. Evidence-based guidelines from ESPGHAN and NASPGHAN for Helicobacter pylori infection in children. J Pediatr Gastroenterol Nutr 2011 Aug;53(2):230-43. [147 references] PubMed External Web Site Policy
 
 
Guideline Status
This is the current release of the guideline.
This guideline updates a previous version: Gold BD, Colletti RB, Abbott M, Czinn SJ, Elitsur Y, Hassall E, Macarthur C, Snyder J, Sherman PM. Helicobacter pylori infection in children: recommendations for diagnosis and treatment. J Pediatr Gastroenterol Nutr 2000 Nov;31(5):490-7.


J Pediatr Gastroenterol Nutr. 2011 Aug;53(2):230-43. doi: 10.1097/MPG.0b013e3182227e90.

Evidence-based guidelines from ESPGHAN and NASPGHAN for Helicobacter pylori infection in children.

Source

Dr von Haunersches Kinderspital, Ludwig-Maximilians-University of Munich, Munich, Germany. sibylle.koletzko@med.uni-muenchen.de

Abstract

OBJECTIVE:

As the clinical implications of Helicobacter pylori infection in children and adolescents continue to evolve, ESPGHAN and NASPGHAN jointly renewed clinical guidelines using a standardized evidence-based approach to develop updated recommendations for children and adolescents in North America and Europe.

METHODS:

An international panel of 11 pediatric gastroenterologists, 2 epidemiologists, 1 microbiologist, and 1 pathologist was selected by societies that developed evidence-based guidelines based on the Delphi process with anonymous voting in a final face-to-face meeting. A systematic literature search was performed on 8 databases of relevance including publications from January 2000 to December 2009. After excluding nonrelevant publications, tables of evidence were constructed for different focus areas according to the Oxford classification. Statements and recommendations were formulated in the following areas: whom to test, how to test, whom to treat, and how to treat. Grades of evidence were assigned to each recommendation based on the GRADE system.

RESULTS:

A total of 2290 publications were identified, from which 738 were finally reviewed. A total of 21 recommendations were generated, and an algorithm was proposed by the joint committee providing evidence-based guidelines on the diagnostic workup and treatment of children with H pylori infection.

CONCLUSIONS:

These clinical practice guidelines represent updated, best-available evidence and are meant for children and adolescents living in Europe and North America, but they may not apply to those living on other continents, particularly in developing countries with a high H pylori infection rate and limited health care resources.
PMID:
21558964
[PubMed - indexed for MEDLINE]

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