CDC Features - High Flu Activity Continues Nationwide

CDC Features - High Flu Activity Continues Nationwide

Influenza

• CDC information: High flu activity continues nationwide
• CDC information: If you get a flu shot, you’re 60% less likely to get sick & spread flu to others. Learn more
• CDC information: It’s not too late to get flu vaccine, but our second line of defense, prompt treatment, also important
• CDC information: People with certain genetic diseases are at high risk for serious illness from flu.  Find out more
• The role of host genetics in susceptibility to influenza: A systematic review.
  Horby P et al. PLoS One 2012
• Genetic basis of pathogenicity of influenza: 1. Genes in humans associated with more severe influenza 2. A new genetic virological factor in influenza viruses that modulates the host response. ECDC Review 2012
• CDC study: A pilot study of host genetic variants associated with influenza-associated deaths among children and young adults.
  Ferdinands JM, Denison AM, Dowling NF, et al. Emerg Infect Dis. 2011 Dec;17(12):2294-302.
• CDC study: Innate immune function and mortality in critically ill children with influenza: A multicenter study
  Hall MW, Geyer SM, Guo CY, et al. Crit Care Med. 2013 Jan;41(1):224-236.
• Did you know that 10 human genes have been reported with risk or severity of human influenza? To find out more, please visit the HuGE Navigator
• Interferon-induced transmembrane protein-3 genetic variant rs12252-C is associated with severe influenza in Chinese individuals
  Yong-Hong Zhang, Yan Zhao, Ning Li, Yan-Chun Peng, et al. Nature Communications 4:1418 Jan 29
  
  • Genetics may explain severe flu in Chinese people, Yahoo News, Jan 29