Doxycycline Shortage
Doxycycline and Tetracycline Shortage Update
The U.S. Food and Drug Administration (FDA) continues to report that doxycycline is available in limited supply and tetracycline is unavailable. If tetracycline or doxycycline is not available, other alternative regimens for young sexually active patients diagnosed with epididymitis are outlined below and described in the 2010 STD Treatment Guidelines. For additional recommendations and alternative regimens for syphilis in nonpregnant patients with a penicillin allergy, please contact a specialist or local health department. (March 1, 2013)Update: Tetracycline Shortage Notice
Update to the recently announced doxycycline shortage -- According to the U.S. Food and Drug Administration (FDA), tetracycline is currently unavailable. If tetracycline or doxycycline is not available, other alternative regimens for epididymitis and for syphilis in nonpregnant patients with a penicillin allergy are described in the 2010 STD Treatment Guidelines. For additional recommendations, please contact a specialist or local health department. (February 8, 2013)Chlamydia and Nongonococcal urethritis
Azithromycin 1 g orally in a single dose
Gonorrhea
Ceftriaxone 250 mg IM in a single dose
PLUS
Azithromycin 1 g orally in a single dose
Syphilis (penicillin allergic)
Primary or secondary syphilis
Tetracycline 500 mg orally four times daily for 14 days
Late latent syphilis
Tetracycline 500 mg orally four times daily for 28 days
Epididymitis
Ceftriaxone 250 mg IM in a single dose
PLUS
Azithromycin 1 g orally in a single dose
PLUS
Levofloxacin 500 mg orally once daily for 10 days
Pelvic Inflammatory Disease*
Ceftriaxone 250 mg IM in a single dose
PLUS
Clindamycin 450 mg orally four times daily for 14 days
WITH OR WITHOUT
Metronidazole 500 mg orally twice a day for 14 days
*see STD Treatment Guidelines for additional regimens
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