Genotype GI.6 Norovirus, United States, 201... [Emerg Infect Dis. 2013] - PubMed - NCBI

Genotype GI.6 Norovirus, United States, 201... [Emerg Infect Dis. 2013] - PubMed - NCBI

Emerg Infect Dis. 2013 Aug;19(8):1317-20. doi: 10.3201/eid1908.130445.

Genotype GI.6 Norovirus, United States, 2010-2012.

Leshem E, Barclay L, Wikswo M, Vega E, Gregoricus N, Parashar UD, Vinjé J, Hall AJ.

Abstract

We report an increase in the proportion of genotype GI.6 norovirus outbreaks in the United States from 1.4% in 2010 to 7.7% in 2012 (p<0 .001="" and="" by="" care="" characterized="" compared="" foodborne="" gi.6="" non-gi.6="" non-health="" outbreaks="" p="" seasonality="" settings.="" summer="" transmission="" were="" with="">

KEYWORDS:

GI.6 genotype, Norovirus, United States, gastroenteritis, outbreak, surveillance, viruses

PMID:

23876252

[PubMed - in process]

PMCID:

PMC3739519

Free PMC Article

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Figure 1

Phylogenetic typing results for GI.6 noroviruses, United States, 2010–2012. Representative outbreak nucleotide sequences were genotyped by region D (5). Sequences were downloaded, trimmed, and analyzed as described (5). In brief, a 3-parameter model, TPM1, with equal frequencies and invariable sites was run in PhyML 3.0 (www.atgc-montpellier.fr/phyml/binaries.php) as determined by jModel test by using the corrected Akaike information criterion. The best of 5 random trees was used to start the analysis, and the approximate likelihood ratio test was used for branch support. GI.6 reference sequences (GenBank accession nos. GQ856463| GI.6 Beijing and AJ277615| GI.6 Sindlesham) were included. Two clusters of genetically related outbreaks (cluster A and cluster B) are marked by brackets. *The distance of GI.1 Norwalk to the nearest GI.6 cluster is 2.29 substitutions per site. Scale bar indicates nucleotide substitutions per site for the phylogenetic tree.

Genotype GI.6 Norovirus, United States, 2010-2012

Emerg Infect Dis. 2013 August;19(8):1317-1320.