Healthy Blood Flow Seen a Year After Face Transplants

Study of three patients found 'excellent' circulation in transplanted tissue

By Robert Preidt

Wednesday, December 4, 2013

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WEDNESDAY, Dec. 4, 2013 (HealthDay News) -- The blood vessels in face transplant patients reorganize themselves after the procedure, researchers report.
During a full face transplant, the recipient's major arteries and veins are connected to those in the donor face to ensure healthy circulation. Because the procedure is new, not much was known about the blood vessel changes that occur to help blood make its way into the transplanted tissue.
The development of new blood vessel networks in transplanted tissue is vital to face transplant surgery success, the investigators pointed out in a news release from the Radiological Society of North America (RSNA).
The researchers analyzed blood vessels in three face transplant patients one year after they had the procedure at Brigham and Women's Hospital in Boston. All three had excellent blood flow in the transplanted tissue, the team found.
"We assumed that the arterial blood supply and venous blood return was simply from the connections of the arteries and the veins at the time of the surgery," study co-author Dr. Frank Rybicki, director of the hospital's Applied Imaging Science Laboratory, said in the news release.
It turns out this is not the case, the researchers noted.
"The key finding of this study is that, after full face transplantation, there is a consistent, extensive vascular reorganization that works in concert with the larger vessels that are connected at the time of surgery," study co-author Dr. Kanako Kumamaru, a research fellow in the laboratory, said in the news release.
The study was scheduled for presentation Wednesday at the RSNA's annual meeting, in Chicago. Data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

SOURCE: Radiological Society of North America, news release, Dec. 4, 2013

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