Public Health Sciences

Genomics|Update|Current

Public Health Sciences

Accurate and robust prediction of genetic relationship from whole-genome sequences 
Hong Li, et al. PloS One February 28, 2014

Assessing single nucleotide variant detection and genotype calling on whole-genome sequenced individuals.
Cheng AY, et al. Bioinformatics. 2014 Feb 27.

Biomarker profiling by nuclear magnetic resonance spectroscopy for the prediction of all-cause mortality: An observational study of 17,345 persons
Fisher K, et al. PLoS Med 2014 Feb 25

Economic utility of a blood-based genomic test for the assessment of patients with symptoms suggestive of obstructive coronary artery disease 
Hochheiser LI, et al. Popul Health Manag 2014 Feb

Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV
Tebas P, et al. N Engl J Med. 2014 Mar 12

Engineering cellular resistance to HIV
Kay M and Walker B N Engl J Med 2014; 370:968-969 March 6, 2014

A genotype-first approach to defining the subtypes of a complex disease. 
H Stessman, Cell, February 2014

Harvard Personal Genome Project: lessons from participatory public research  [PDF 460.59 KB]
Madeleine P Ball et al. Genome Medicine, February 2014

A higher mutational burden in females supports a "female protective model" in neurodevelopmental disorders. 
Sébastien Jacquemont et al. Am J Hum Genetics, February 26, 2014

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes
Jason Flannick et al. Nature Genetics, March 2, 2014

Rare mutation kills off gene responsible for diabetes, by Gina Kolata, The New York Times, Mar 2

A penalized robust method for identifying gene–environment interactions
Xingjie Shi et al. Genetic Epidemiology, February 2014