The Epigenetic Clock and Health: Hope and Hype - February 2, 2015

Genomics|Features|Epigenetics

Epigenetics

The Epigenetic Clock and Health: Hope and Hype - February 2, 2015

DNA methylation age of blood predicts all-cause mortality in later life. 
Riccardo E Marioni et al. Genome Biology, January 30, 2015

Google Calendar gives count-down remaining life expectancy based on DNA methylation, by Cecile Janssens , Blog Post, Jan 31

How does the body know how old it is? Introducing the epigenetic clock hypothesis.
Mitteldorf J. Interdiscip Top Gerontol. 2015;40:49-62.

Biomarkers and ageing: The clock-watcher.
Gibbs WW. Nature. 2014 Apr 10;508(7495):168-70

The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936.
Marioni RE, et al. Int J Epidemiol. 2015 Jan 22

Circadian clocks, epigenetics, and cancer.
Masri S, et al. Curr Opin Oncol. 2015 Jan;27(1):50-

DNA methylation age of human tissues and cell types.
Horvath S. Genome Biol. 2013;14(10):R115.

Epigenetics: Linking the Environment to Human Disease - October 9, 2014

New CDC blog post: Epigenetics and public health: Why we should pay attention

Epigenetics/inheritance and the environment. The genome's dynamic response to the environment,Educational resources from the National Library of Medicine

Diverse epigenetic mechanisms of human disease. 
Brookes E, Shi Y. Annu Rev Genet. 2014 Sep 5.

Epigenome: Biosensor of cumulative exposure to chemical and nonchemical stressors related to environmental justice. 
Kenneth Olden, et al. Am Journal Public Health, October 2014

Epigenetics: relevance and implications for public health. 
Rozek LS, et al. Annu Rev Public Health. 2014;35:105-22

Epigenetics across the human lifespan
Antonei B. Csoka et al.  Front. Cell Dev. Biol. August 2014

Epigenetics. Looking beyond our DNA. Horizons in bioscience.  [PDF 10.63 MB] 
The Federation of American Societies for Experimental Biology (FASEB) (2014)

Do early paternal exposures to lifestyle factors such as smoking increase the risk of chronic diseases in the offspring?
Adelheid Soubry et al. European Journal Human Genetics, October 8, 2014

High-resolution digital profiling of the epigenome.
Gabriel E. Zentner et al. Nature Reviews Genetics, 09 October 2014

Fast facts about epigenetics,  [PDF 537.22 KB] from the University of Washington in Seattle