Myopia: Public Health and Genomic Insights - March 23, 2015

Genomics|Features|Myopia

Myopia

Myopia: Public Health and Genomic Insights - March 23, 2015

The myopia boom
Short-sightedness is reaching epidemic proportions. Some scientists think they have found a reason why. 
By Elie Dolgin, Nature News, Mar 19

Facts about myopia, from the National Eye Institute

Risk factors for myopia include family history, from the Mayo Clinic

Check out genes reported in relation to myopia, from the HuGE Navigator

Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci.
Simpson CL et al. PLoS ONE 2014 (9) e107110

Genome-wide association study success in ophthalmology.
Mackey DA et al. Curr Opin Ophthalmol 2014 Sep (5) 386-93

Impact of parental history of myopia on the development of myopia in mainland china school-aged children.
Lim LT et al. Ophthalmol Eye Dis 2014 31-5

Meta-analysis of the association between lumican gene polymorphisms and susceptibility to high Myopia.
He M et al. PLoS ONE 2014 (6) e98748

Genome-wide association studies of refractive error and myopia, lessons learned, and implications for the future.
Hysi PG et al. Invest. Ophthalmol. Vis. Sci. 2014 May (5) 3344-51

Epidemiology of myopia.
Foster PJ et al. Eye (Lond) 2014 Feb (2) 202-8

Genetic and environmental effects on myopia development and progression.
Goldschmidt E et al. Eye (Lond) 2014 Feb (2) 126-33

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.
Cheng CY et al. Am. J. Hum. Genet. 2013 Aug 8. (2) 264-77

Education influences the role of genetics in myopia.
Verhoeven VJ M et al. Eur. J. Epidemiol. 2013 Dec (12) 973-80

Advances in the genomics of common eye diseases.
Cooke BJN et al. Hum. Mol. Genet. 2013 Oct 15. (R1) R59-65