Chronic Fatigue Syndrome: Genomics and Public Health - July 1, 2015

Chronic Fatigue Syndrome

Chronic Fatigue Syndrome: Genomics and Public Health - July 1, 2015

CDC and Related Info

• Chronic Fatigue Syndrome Awareness Day
• Chronic fatigue syndrome
• Genes reported in relation to chronic fatigue, including genomewide association studies via theHuGE Navigator

Pathway-focused genetic evaluation of immune and inflammation related genes with chronic fatigue syndrome.
Rajeevan MS et al.Hum. Immunol. 2015 Jun 24.

CDC information: Chronic Fatigue Syndrome Awareness Day

Identification of a MicroRNA signature for the diagnosis of fibromyalgia.
Cerdá-Olmedo G et al. PLoS ONE 2015 (3) e0121903

Abnormalities of AMPK activation and glucose uptake in cultured skeletal muscle cells from individuals with chronic fatigue syndrome.
Brown AE et al. PLoS ONE 2015 (4) e0122982

CDC information: Chronic fatigue syndrome is a debilitating and complex disorder 
CFS is characterized by profound fatigue that is not improved by bed rest and that may be worsened by physical or mental activity

Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Redefining an illness,  [PDF 373.58 KB] Institute of Medicine Report, February 2015

Chronic fatigue syndrome gets a new name,  by David Tuller, New York Times, Feb 10

What genes have been reported in relation to risk and outcomes of chronic fatigue syndrome?Check out the HuGE Navigator

Convergent genomic studies identify association of GRIK2 and NPAS2 with chronic fatigue syndrome.
Smith Alicia K et al. Neuropsychobiology 2011 (4) 183-94

Genome-wide analysis of single nucleotide polymorphisms and copy number variants in fibromyalgia suggest a role for the central nervous system.
Docampo Elisa et al. Pain 2014 Jun (6) 1102-9

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