AGING: June 23-30, 2016

Public Health Genomics Knowledge Base (v1.0)

June 23-30, 2016

AGING

Last Updated: Jun 24, 2016

• APOE and aging-related cognitive change in a longitudinal cohort of men.
  Rantalainen Ville, et al. Neurobiology of aging 2016 8 151-8
• Impaired fasting glucose is associated with increased regional cerebral amyloid.
  Morris Jill K, et al. Neurobiology of aging 2016 8 138-42
• Telomere-associated aging disorders.
  Opresko Patricia L et al. Ageing research reviews 2016 May
• The Healthy Aging Data Portal 
• Analyses MAPT, GRN, and C9orf72 mutations in Chinese patients with frontotemporal dementia.
  Tang Min, et al. Neurobiology of aging 2016 5
• The Healthy Aging Data Portal 
• Focus on Aging
  Cell Metabolism
• Genes for a ‘Wellderly’ Life
  JSK Kauwe et al, Cell Metabolism, June 2016
• Genetic Variants of the FADS Gene Cluster Are Associated with Erythrocyte Membrane LC PUFA Levels in Patients with Mild Cognitive Impairment.
  Schuchardt J P, et al. The journal of nutrition, health & aging 2016 0 (6) 611-20
• Short Telomere Length and Ischemic Heart Disease: Observational and Genetic Studies in 290 022 Individuals.
  Scheller Madrid Alexander, et al. Clinical chemistry 2016 6
• Determinants of iron accumulation in the normal aging brain.
  Pirpamer Lukas, et al. Neurobiology of aging 2016 7 149-55
• Strong association between glucocerebrosidase mutations and Parkinson's disease in Sweden.
  Ran Caroline, et al. Neurobiology of aging 2016 5
• Association between Obese Phenotype and Mildly Reduced eGFR among the General Population from Rural Northeast China.
  Yu Shasha, et al. International journal of environmental research and public health 2016 0 (6)
• Plasma apolipoprotein J as a potential biomarker for Alzheimer's disease: Australian Imaging, Biomarkers and Lifestyle study of aging.
  Gupta Veer Bala, et al. Alzheimer's & dementia (Amsterdam, Netherlands) 2016 0 18-26
• Selective familiarity deficits in otherwise cognitively intact aging individuals with genetic risk for Alzheimer's disease.
  Schoemaker Dorothee, et al. Alzheimer's & dementia (Amsterdam, Netherlands) 2016 0 132-9
• Genomic African and Native American Ancestry and Chagas Disease: The Bambui (Brazil) Epigen Cohort Study of Aging.
  Lima-Costa M Fernanda, Macinko James, Mambrini Juliana Vaz de Mello, Peixoto Sérgio Viana, Pereira Alexandre Costa, Tarazona-Santos Eduardo, Ribeiro Antonio Luiz Pinho.PLoS neglected tropical diseases 2016 May (5) e0004724
• Conversion from MCI to AD in patients with the APOE ?4 genotype: Prediction by plasma HCY and serum BDNF.
  Zheng Lei, et al. Neuroscience letters 2016 5
• Exhaustive Genome-Wide Search for SNP-SNP Interactions Across Ten Human Diseases.
  Murk William, et al. G3 (Bethesda, Md.) 2016 5
• Genetic variants in ATP6 and ND3 mitochondrial genes are not associated with aggressive prostate cancer in Mexican-Mestizo men with overweight or obesity.
  Canto Patricia, et al. The aging male : the official journal of the International Society for the Study of the Aging Male 2016 5 1-5
• The Application of Genetic Risk Scores in Age-Related Macular Degeneration: A Review.
  Cooke Bailey Jessica N et al. Journal of clinical medicine 2016 5(3)
• Associations of APOE ?4 With Health and Financial Literacy Among Community-Based Older Adults Without Dementia.
  Stewart Christopher C, et al. The journals of gerontology. Series B, Psychological sciences and social sciences 2016 5
• Relationship between APOE Genotype and Structural MRI Measures throughout Adulthood in the Study of Health in Pomerania Population-Based Cohort.
  Habes M, et al. AJNR. American journal of neuroradiology 2016 5
• APOE Genotype in the Ethnic Majority and Minority Groups of Laos and the Implications for Non-Communicable Diseases.
  Midorikawa Kaoru, et al. PloS one 2016 0 (5) e0155072
• TBK1 is associated with ALS and ALS-FTD in Sardinian patients.
  Borghero Giuseppe, et al. Neurobiology of aging 2016 4
• Accelerated decline in white matter integrity in clinically normal individuals at risk for Alzheimer's disease.
  Rieckmann Anna, et al. Neurobiology of aging 2016 6 177-88
• CAIDE Dementia Risk Score and biomarkers of neurodegeneration in memory clinic patients without dementia.
  Enache Daniela, et al. Neurobiology of aging 2016 6 124-31
• Risk-reducing Apolipoprotein E and Clusterin genotypes protect against the consequences of poor vascular health on executive function performance and change in nondemented older adults.
  McFall G Peggy, et al. Neurobiology of aging 2016 6 91-100
• Excessive folic acid intake and relation to adverse health outcome.
  Selhub Jacob, et al. Biochimie 2016 4
• The role of the melanoma gene MC1R in Parkinson disease and REM sleep behavior disorder.
  Gan-Or Ziv, et al. Neurobiology of aging 2016 4
• Cardiometabolic risk factors predict cerebrovascular health in older adults: results from the Brain in Motion study.
  Tyndall Amanda V, et al. Physiological reports 2016 4 (8)

• CDC Information (6)
• CDC-Authored Pub (2)

• Human (22)
• Pathogen (1)

• Human (3017)
• Pathogen (0)

• Human (14)
• Pathogen (0)

• Guidelines (1)
• Tier Table (0)
• Synthesis (2)

• Implementation (1)

Relevant Resources

• Cancer Genomics and Epidemiology Navigator (CGEN)
• Genetics and Genomics Competencies Center (G2C2)
• NIH Genetic Testing Registry
• NIH MedGen Database
• Online Mendelian Inheritance in Man (OMIM)
• PharmGKB