jueves, 30 de junio de 2016

Breast Cancer Research | Home page

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Featured review: Cancer stem cell metabolism

Even though cancer is now viewed as a stem cell disease, there is still no consensus on the metabolic characteristics of these cells. This review by Maria Peiris-Pagès et al.summarizes the latest findings and discoveries on cancer stem cell metabolism.

Articles

  1. RESEARCH ARTICLE

    Efficacy and safety of palbociclib in combination with letrozole as first-line treatment of ER-positive, HER2-negative, advanced breast cancer: expanded analyses of subgroups from the randomized pivotal trial PALOMA-1/TRIO-18

    Richard S. Finn, John P. Crown, Johannes Ettl, Marcus Schmidt, Igor M. Bondarenko, Istvan Lang, Tamas Pinter, Katalin Boer, Ravindranath Patel, Sophia Randolph, Sindy T. Kim, Xin Huang, Patrick Schnell, Sashi Nadanaciva, Cynthia Huang Bartlett and Dennis J. Slamon
    Published on: 28 June 2016

Meet the Editor-in-Chief

Dr. Lewis A. Chodosh is a physician-scientist who received a BS in Molecular Biophysics and Biochemistry from Yale University, and MD from Harvard Medical School, and a PhD. in Biochemistry from M.I.T. in the laboratory of Dr. Phillip Sharp. He performed his clinical training in Internal Medicine and Endocrinology at the Massachusetts General Hospital, after which he was a postdoctoral research fellow with Dr. Philip Leder at Harvard Medical School. Dr. Chodosh joined the faculty of the University of Pennsylvania in 1994, where he is currently a Professor in the Departments of Cancer Biology, Cell & Developmental Biology, and Medicine. He serves as Chairman of the Department of Cancer Biology, Associate Director for Basic Science of the Abramson Cancer Center, and Director of Cancer Genetics for the Abramson Family Cancer Research Institute at the University of Pennsylvania. Additionally, he is on the scientific advisory board for the Harvard Nurses' Health Studies I and II. 
Dr. Chodosh's research focuses on genetic, genomic and molecular approaches to understanding breast cancer susceptibility and pathogenesis.

FEATURED THEMATIC SERIES - Lobular Breast Cancer

Lobular Breast Cancer
This special series takes a translational view of lobular breast cancer, from bedside to bench and back. The second most common breast cancer subtype, lobular breast cancer displays many unique molecular and clinical properties. Leaders in the field explore the molecular biology, pathology, risk factors, imaging, treatment and prognosis of this breast cancer.

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