Emergence of plasmid-mediated colistin resistance and New Delhi metallo-β-lactamase genes in extensively drug-resistant Escherichia coli isolated f... - PubMed - NCBI

Emergence of plasmid-mediated colistin resistance and New Delhi metallo-β-lactamase genes in extensively drug-resistant Escherichia coli isolated f... - PubMed - NCBI

Diagn Microbiol Infect Dis. 2016 Nov 14. pii: S0732-8893(16)30376-5. doi: 10.1016/j.diagmicrobio.2016.11.005. [Epub ahead of print]

Emergence of plasmid-mediated colistin resistance and New Delhi metallo-β-lactamase genes in extensively drug-resistant Escherichia coli isolated from a patient in Thailand.

Paveenkittiporn W1, Kerdsin A2, Chokngam S3, Bunthi C4, Sangkitporn S1, Gregory CJ5.

Author information

Abstract

We reported a case of Escherichia coli with colistin resistance and an extensively drug-resistant phenotype. Molecular analysis revealed that the isolate carried mcr-1 and multiple β-lactamase genes includingblaNDM1, blaCTX-M-15, blaTEM1, and blaCMY-2. This is the first report of a clinical mcr-1 isolate in Thailand highlighting the urgent need for a comprehensive antimicrobial resistance containment strategy to prevent further spread.

Copyright © 2016 Elsevier Inc. All rights reserved.

KEYWORDS:

Colistin resistance; XDR E.coli; mcr-1

PMID:

 

27894674

 

DOI:

 

10.1016/j.diagmicrobio.2016.11.005

[PubMed - as supplied by publisher]