Hypopharyngeal Cancer Treatment (PDQ®)–Health Professional Version

SECTIONS

Changes to This Summary (12/22/2016)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

General Information About Hypopharyngeal Cancer

Added Lefebvre et al. as reference 24.

Stage II Hypopharyngeal Cancer

Added Lefebvre et al. as reference 4.

Stage III Hypopharyngeal Cancer

Added Lefebvre et al. as reference 5.

Added text to state that concurrent chemotherapy is a standard treatment option for patients with locally advanced hypopharyngeal cancer. Added that a meta-analysis of 93 randomized prospective head and neck cancer trials published between 1965 and 2000 showed a 4.5% absolute survival advantage in the subset of patients who received chemotherapy and radiation therapy (cited Pignon et al. as reference 13 and level of evidence 2A). Also added that patients who received concurrent chemotherapy had a greater survival benefit than those who received induction chemotherapy.

Stage IV Hypopharyngeal Cancer

Added Lefebvre et al. as reference 4.

Added text to state that concurrent chemotherapy is a standard treatment option for patients with locally advanced hypopharyngeal cancer. Added that a meta-analysis of 93 randomized prospective head and neck cancer trials published between 1965 and 2000 showed a 4.5% absolute survival advantage in the subset of patients who received chemotherapy and radiation therapy (cited Pignon et al. as reference 18 and level of evidence 2A). Also added that patients who received concurrent chemotherapy had a greater survival benefit than those who received induction chemotherapy.

This summary is written and maintained by the PDQ Adult Treatment Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ® - NCI's Comprehensive Cancer Database pages.

< Previous section
Recurrent and Metastatic Hypopharyngeal Cancer

Next section >
About This PDQ Summary