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Featured review: Response biomarkers to tailor cancer drug therapy

Amin & Bathe BMC Cancer 2016 - CC

Response biomarkers represent an attractive, yet under-explored alternative to radiographic tests such as CT and PET that are currently used to evaluate individual response to treatment and inform tailored cancer therapy. Shahil Amin and Frank Bathe review the state of the art on treatment response assessment, and propose a framework for response biomarker discovery.

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Featured article: Community-based football for men with prostate cancer, a study protocol

Jayel Aheram CC

Can football training delivered at local football clubs help improve the wellbeing and quality of life of men diagnosed with prostate cancer? A Dutch randomized controlled trial is set to find out.

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1. RESEARCH ARTICLE

   The effect of a germline mutation in the APC gene on β-catenin in human embryonic stem cells

   Nofar Yedid, Yael Kalma, Mira Malcov, Ami Amit, Revital Kariv, Michal Caspi, Rina Rosin-Arbesfeld and Dalit Ben-Yosef

   Published on: 23 December 2016
2. RESEARCH ARTICLE

   Agonists and knockdown of estrogen receptor β differentially affect invasion of triple-negative breast cancer cells in vitro

   Susanne Schüler-Toprak, Julia Häring, Elisabeth C. Inwald, Christoph Moehle, Olaf Ortmann and Oliver Treeck

   Published on: 21 December 2016
3. RESEARCH ARTICLE

   Oral cancer incidence and survival rates in the Republic of Ireland, 1994-2009

   Hala Ali, Sarah-Jo Sinnott, Paul Corcoran, Sandra Deady, Linda Sharp and Zubair Kabir

   Published on: 20 December 2016
4. RESEARCH ARTICLE

   Knockdown of ST6Gal-I increases cisplatin sensitivity in cervical cancer cells

   Xiaopeng Zhang, Chunchen Pan, Lei Zhou, Zhaogen Cai, Shufang Zhao and Donghong Yu

   Published on: 16 December 2016
5. RESEARCH ARTICLE

   Is upfront stereotactic radiosurgery a rational treatment option for very elderly patients with brain metastases? A retrospective analysis of 106 consecutive patients age 80 years and older

   Shoji Yomo and Motohiro Hayashi

   Published on: 15 December 2016

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