Prostate Cancer, Nutrition, and Dietary Supplements (PDQ®)–Health Professional Version

SECTIONS

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Green Tea

Revised text to state that green tea catechins (GTCs) include (−)-epigallocatechin-3-gallate (EGCG), (−)-epicatechin (EC), (−)-epigallocatechin (EGC), (−)-epicatechin-3-gallate (ECG), and oligomeric proanthocyanidins derived from these catechin monomers.

Revised text to state that GTCs include EGCG, EC, EGC, ECG, and oligomeric proanthocyanidins derived from these catechin monomers.

Pomegranate

Revised text to state that various components of the pomegranate fruit contain minerals and bioactive polyphenolic compounds, in particular structurally distinct ellagitannins and derivatives, such as alpha-/beta-punicalagin, punicalin, and punigluconin.

Revised text to state that the peel makes up 50% of the fruit and contains minerals and a number of bioactive polyphenolic compounds, in particular structurally distinct ellagitannins and derivatives, such as alpha-/beta-punicalagin, punicalin, and punigluconin. Also added text to state that it has been shown that conversion of pomegranate ellagitanninas by gut microbes produces a variety of metabolites, such as the urolithins (cited Yuan et al. as reference 5).

The Human Studies subsection was extensively revised.

Selenium

Added text about a case-cohort analysis of 1,434 men in the Selenium and Vitamin E Cancer Prevention Trial (SELECT) who underwent analysis of single nucleotide polymorphisms (SNPs) in 21 genes (cited Chan et al. as reference 46).

Vitamin E

Added text about a case-cohort analysis of 1,434 men in the SELECT who underwent analysis of SNPs in 21 genes (cited Chan et al. as reference 24).

Multicomponent Therapies

The Pomi-T (Pomegranate, Green Tea, Broccoli, and Turmeric) subsection was renamed from Pomegranate, Green Tea, Broccoli, and Turmeric.

This summary is written and maintained by the PDQ Integrative, Alternative, and Complementary Therapies Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ® - NCI's Comprehensive Cancer Database pages.

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