lunes, 13 de marzo de 2017

Whole genome sequencing of a large panel of contemporary Neisseria gonorrhoeae clinical isolates indicates that a wild-type mtrA gene is common: im... - PubMed - NCBI

Whole genome sequencing of a large panel of contemporary Neisseria gonorrhoeae clinical isolates indicates that a wild-type mtrA gene is common: im... - PubMed - NCBI



 2017 Feb 13. pii: AAC.00262-17. doi: 10.1128/AAC.00262-17. [Epub ahead of print]

Whole genome sequencing of a large panel of contemporary Neisseria gonorrhoeae clinical isolates indicates that a wild-type mtrA gene is common: implications for inducible antimicrobial resistance.

Abstract

Previous studies (1) have shown that the expression of the mtrCDE efflux pump operon is inducible at the transcriptional level in gonococci during incubation in sub-lethal concentrations of the nonionic detergent Triton X-100, which along with antibiotics, bile salts, progesterone and antimicrobial peptides, is a substrate of the MtrCDE efflux pump (2).….

PMID:
 
28193667
 
DOI:
 
10.1128/AAC.00262-17

No hay comentarios:

Publicar un comentario en la entrada