Increasing the age limit for Lynch syndrome genetic testing may save lives

Last Posted: Jun 01, 2017

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• Increasing the age limit for Lynch syndrome genetic testing may save lives  
  Science Magazine, May 29, 2017
• Predictive model for high-frequency microsatellite instability in colorectal cancer patients over 50 years of age.  
  Fujiyoshi Kenji et al. Cancer medicine 2017 May
• Quality of life following prophylactic gynecological surgery: experiences of female Lynch mutation carriers.  
  Etchegary Holly et al. Familial cancer 2017 May
• Dissecting microsatellite instability in colorectal cancer: one size does not fit all  
  RM Samstein et al, Genome Medicine, May 24, 2017
• Aiming to Prevent Hereditary Cancers, Researchers Focus on Lynch Syndrome  
  NCI, May 2017
• Clinicopathologic Characteristics of Endometrial Cancer in Lynch Syndrome: A French Multicenter Study.  
  Rossi Léa et al. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2017 Jun 27(5) 953-960
• Comparison of lifestyle, hormonal and medical factors in women with sporadic and Lynch syndrome-associated endometrial cancer: A retrospective case-case study.  
  Aaltonen Mari H et al. Molecular and clinical oncology 2017 May 6(5) 758-764
• Multigene Panel Testing Provides a New Perspective on Lynch Syndrome.  
  Espenschied Carin R et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2017 May JCO2016719260
• Suspected Lynch syndrome associated MSH6 variants: A functional assay to determine their pathogenicity.  
  Houlleberghs Hellen et al. PLoS genetics 2017 May 13(5) e1006765
• FDA grants accelerated approval to pembrolizumab for first tissue/site agnostic indication  
  FDA, May 23, 2017
• Multigene Panel Testing Provides a New Perspective on Lynch Syndrome  
  CR Espenschied, et al. J Clin Oncology, May 2017
• AGO Austria recommendation on screening and diagnosis of Lynch syndrome (LS).  
  Zeimet Alain G et al. Archives of gynecology and obstetrics 2017 May
• Development and Validation of the PREMM5 Model for Comprehensive Risk Assessment of Lynch Syndrome.  
  Kastrinos Fay et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2017 May JCO2016696120
• Identifying Lynch Syndrome in Women Presenting With Endometrial Carcinoma Under the Age of 50 Years.  
  Anagnostopoulos Antonios et al. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2017 May
• New, simple online tool guides genetic testing for Lynch syndrome  
  Dana Farber, May 2017
• Universal molecular screening does not effectively detect Lynch syndrome in clinical practice.  
  Brennan Beatrice et al. Therapeutic advances in gastroenterology 2017 Apr 10(4) 361-371

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