Slight Changes to Broadly Neutralizing HIV Antibody Yield Great Dividends | NIH: National Institute of Allergy and Infectious Diseases

Slight Changes to Broadly Neutralizing HIV Antibody Yield Great Dividends | NIH: National Institute of Allergy and Infectious Diseases

Thursday February 22, 2018

Slight Changes to Broadly Neutralizing HIV Antibody Yield Great Dividends

NIAID scientists have demonstrated that slight changes to a powerful, naturally occurring HIV antibody help it last longer in the human body while counteracting the virus just as well in the laboratory. These characteristics could reduce the cost and increase the convenience of giving people antibodies for HIV prevention because fewer doses of an antibody may achieve the same protective effect. Now scientists at NIAID and elsewhere are testing the same changes in other broadly neutralizing HIV antibodies to develop additional candidates for HIV prevention.